The proposed National Action Plan for Health Security (NAPHS) aimed to improve the health, social and economic status by reducing health security threats through multi-sectorial coordination; quality human infrastructure and financial resources; and health management system that assures continuous community participation and engagement. Several objectives and activities has planned under the 46 JEE indicators of the 19 thematic areas to improve the national health security and expected to be implemented in a one health approach within the next five years (2018-2022).